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These drugs also assist in weight loss and have a lower risk of causing acid reflux
Glia 61 , 14711487 (2013)
They all work by leveraging the body's own incretin system to improve glucose regulation, and most of them produce significant weight loss as a beneficial side effect, or in some cases, as the primary intended effect
Then a pH change cleaves the linker, freeing the lanifibranor moiety to escape to the nucleus and activate PPARs
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